Timothy Wilson Spencer was identified as the man who raped and strangled five young women in Virginia. With the use of DNA profiling, an innocent man is freed and the real killer is convicted.

After a Philadelphia Convention, 180 Legionnaires contract pneumonia-like symptoms and 29 of them die. The determination of one scientist helps to determine the cause of this deadly disease.

On the night of May 22, 1992, Betty Wilson returned home after a meeting. She walked up the stairs to the bedroom and discovered her husband, lying in a pool of blood. Jack Wilson had obviously been murdered... but how? And by whom?

Between 1985 and 1988, 18 people were choked, molested, and left for dead in the remote desert mountains of California. The only witnesses were the insects, which proved to play an important role in solving the crimes and bringing the killer to justice.

In 1971, John List left a note with the bodies of his mother, wife, and three children in his mansion ballroom before he disappeared. To solve the case, detectives only had an outdated photograph of List.

Ten bodies had been found between the months of May and November 1984, in Florida. A 17-year-old female named Lisa McVey was abducted but released, leading police to the perpetrator, Bobbie Joe Long.

Eileen and Derrick Severs disappeared from their home in the small village of Hambleton in Great Britain and police found evidence that suggested foul play. Careful analysis of a soil sample would tell investigators what happened to the couple.

The single most deadly automobile accident in American history happened along a highway long known for dense, thick fog. Investigators set out to determine if the fog was a natural phenomenon or the result of something else.

While Earl Morris was vacationing in California, he learned his wife had gone missing from their home in Arizona. The search for Ruby Morris involved dozens of personnel and the results of that investigation surprised everyone... especially Earl Morris.

The flu-like symptoms of a mother and her children proved to be something more serious: thallium poisoning. After the mother's death, investigators turned their attention to finding the killer.

A farmer came upon a chilling sight of a severed lambs head impaled on his fence post along with a note which read, 'You next.' The author of the note didn't elaborate on why the farmer had been targeted, but between the lines, he'd said plenty.

An infant was rushed to the emergency room with serious breathing problems. Within months, there were more than 30 cases. Doctors searched frantically for the cause and a cure.

Shortly after daybreak in Vancouver, British Columbia, a fire was set in a dumpster. No one saw either the arsonist or the fire. There was more than garbage in the container, and it would take sophisticated science to find the evidence in the ashes.

Two people in Seattle, Washington died after taking an over-the-counter pain reliever; lab analysis of the pills showed they were tainted with a lethal concentration of cyanide.

On October 15, 1985, two bomb explosions rocked Salt Lake City and resulted in two deaths. A third explosion occurred the next day. When they turned to forensic science for help, they uncovered an almost unbelievable story of forgery, fraud, and murder.

After a day of fishing in a small village in Switzerland, a teenage boy did not return home as planned. The investigation revealed some important microscopic evidence in the water near where he was last seen. But would it be enough for them to find him?

Eleven-month-old Chad Shelton was admitted to the hospital with unexplained bleeding and later died. Investigators and scientists frantically search for a cause when others from the same house fell ill.

In the mid-1980s, bodies of nude woman were found on remote hill of California. The police got a break when a known prostitute escaped an attacker and was able to identify him and his automobile.

In 1987, a human skull and some bones were discovered at a Boy Scout Camp near Farmington, Missouri. A facial reconstruction aided the investigators in this case.

A serial bomber was waging a vendetta against the legal profession: A judge, two attorneys and even a courthouse had been targeted. Employing a range of forensic techniques, investigators used evidence from the bombs to lead them to the perpetrator.

Robert Sims returned home after working the night shift, and found his wife, Paula, unconscious on the kitchen floor. Their two-year-old son, Randy, was asleep in an upstairs bedroom, but their six-week-old daughter, Heather, was missing.